Abstract: Jet noise is an important contributor to overall aircraft noise. The flow near the jet nozzle is a spatially developing mixing layer and influences flow dynamics further downstream. The present study focuses on the influence of inflow conditions on mixing layer development and noise generation mechanisms. Large-eddy simulations of spatially developing, turbulent mixing layers with splitter plate included in the computational domain are presented. Different inflow condition cases with initially laminar boundary layers (abbreviated as LBL) and turbulent boundary layers (abbreviated as TBL) are considered. Effect of heating keeping the velocity ratio fixed is analyzed for both. It is observed that with heating, the initial instability is accelerated but the saturation self-similar amplitude of Reynolds stress components do not vary. The saturation amplitudes of density fluctuations were found to increase proportionally to difference in free-stream densities whereas near-field pressure fluctuations were found to decrease with heating. A simple scaling is suggested for the near-field pressure fluctuation amplitude. For LBL, sound radiation is observed in downstream direction peaked roughly at 30 degrees. The vortex pairing and breakdown to turbulence contribute significantly to the radiated sound. For TBL, the acoustic field near the shear layer is significantly weaker and noise due to passage of boundary layer eddies over the trailing edge is observed. For both the cases, a reduction in overall sound pressure levels in the far-field is observed with heating.  The analysis of relative importance of Reynolds stress and enthalpy flux covariance tensor components, that is, the sound source terms in the generalized acoustic analogy, is presented to explain the effects of heating.